Reach Us +44-1764-910199

Abstract

Prognostic Value of Serum Cholesterol and Triglyceride in Septic and Non-septic Patients: Randomized Double-blinded Study

Aims Is to evaluate the difference between the level of serum cholesterol and triglyceride in septic and non-septic patients and to find a correlation between the level of cholesterol and triglyceride and Acute Physiology and Chronic Health Evaluation Score and quick Sequential Organ Failure Assessment score. Materials and Methods 95 patients admitted to the SICU, septic patients (group S, n=50) or non-septic patients (NS, n=45). Main outcome measures: length of ICU stay, 28-day mortality, days on mechanical ventilation, (APACHE II) scores, (qSOFA) scores, serum cholesterol, and triglyceride on days 0 and on 1st, 3rd, 7th,10th and 14th day. Result Cholesterol level (mg/dL) Day 0: It was statistically significant lower in septic group (S) compared to the non-septic group (NS); it was 119.4 ± 29.33 versus 131.2 ± 35.37 (p value=0.037). Day 1: It was statistically significantly lower in the septic group (S): 103.6 ± 29.19 than the non-septic group (NS):123.56 ± 36.50 (p value ˂0.001). Day 3: It was statistically significantly lower in the septic group (S) 80.7 ± 26.87 than in the non-septic group (NS) 124.84 ± 32.4 (p value <0.001). Triglyceride level (mg/dL): Day 1: Was statistically significantly higher in the septic group (S): 151.5 ± 54.79, than the non-septic group (NS): 112.14 ± 33.02, (p value <0.001). Day 3: It was statistically significant higher in the septic group (S):185.1 ± 43.1 than the non-septic group (NS): 113.5 ± 39.56), (p value <0.001). Conclusion Cholesterol levels decreased markedly and triglyceride levels increased in patients with sepsis compared to non-septic patients, in the septic patients there was increasing in length of ICU stay, higher qSOFA, and APACHE II scores.


Author(s):

Doaa Rashwan, Samaa Abou Al Kassem Rashwan, Wael Fathy Hassan and Doaa Moaz Sayem



Abstract | PDF

Share this  Facebook  Twitter  LinkedIn  Google+
Flyer image

Abstracted/Indexed in

  • Index Copernicus
  • Google Scholar
  • WorldCat
  • Geneva Foundation for Medical Education and Research
  • Secret Search Engine Labs